ERPNext Hospitality module is designed to handle workflows for Hotels and Restaurants. This is still in early development stage.
The Restaurant module in ERPNext will help you manage a chain of restaurants. You can create Restaurants, Menus, Tables, Reservations and a manage Order Entry and Billing.
The Hotels module in ERPNext will help you manage creating Hotel Rooms, create Hotel Room Reservation. It will also help in creating Invoice from hotel room reservation